Original Papers

  1. Araoka, H., Baba, M., Okada, C., Kimura, M., Sato, T., Yatomi, Y., Moriya, K., and Yoneyama, A. Risk factors for recurrent Helicobacter cinaedi bacteremia and the efficacy of selective digestive decontamination with kanamycin to prevent recurrence. Clin. Infect. Dis., in press.
  2. Araoka, H., Baba, M., Okada, C., Kimura, M., Sato, T., Yatomi, Y., Moriya, K., and Yoneyama, A. First evidence of bacterial translocation from the intestinal tract as a route of Helicobacter cinaedi bacteremia. Helicobacter 23:e12458, 2018.
  3. Hikita, H., Sato, M., Sato, M., Soroida, Y., Kobayashi, T., Gotoh, H., Iwai, T., Nakagomi, R., Tateishi, R., Komuro, T., Sone, S., Koike, K., Yatomi, Y., and Ikeda, H. Disappearance of Perihepatic lymph node enlargement achieving hepatitis C viral eradication using direct acting antivirals. J. Viral Hepat. 15: 329-334, 2018.
  4. Hiyama, N., Ando, T., Maemura, K., Sakatani, T., Amano, Y., Watanabe, K., Kage, H., Yatomi, Y., Nagase, T., Nakajima, J., and Takai D. Glutamate-cysteine ligase catalytic subunit is associated with cisplatin resistance in lung adenocarcinoma. Jpn. J. Clin. Oncol. 48: 303-307, 2018.
  5. Honjo, M., Igarashi, N., Kurano, M., Yatomi, Y., Igarashi, K., Kano, K., Aoki, J., Weinreb, R.N., and Aihara, M. Autotaxin-Lysophosphatidic Acid Pathway in Intraocular Pressure Regulation and Glaucoma Subtypes. Invest. Ophthalmol Vis. Sci. 59: 693-701, 2018.
  6. Honjo, M., Igarashi, N., Nishida, J., Kurano, M., Yatomi, Y., Igarashi, K., Kano, K., Aoki, J., and Aihara, M. Role of the Autotaxin-LPA Pathway in Dexamethasone-Induced Fibrotic Responses and Extracellular Matrix Production in Human Trabecular Meshwork Cells. Invest. Ophthalmol. Vis. Sci. 59: 21-30, 2018.
  7. Ikeda., H., Kobayashi, M., Kumada, H., Enooku, K., Koike, K., Kurano, M., Sato, M., Nojiri, T., Kobayashi, T., Ohkawa, R., Shimamoto, S., Igarashi, K., Aoki, J., and Yatomi, Y. Performance of autotaxin as a serum marker of liver fibrosis. Ann. Clin. Biochem. 55: 469-477, 2018.
  8. Igarashi, N., Honjo, M., Kurano, M., Yatomi, Y., Igarashi, K., Kano, K., Aoki, J., and Aihara M.  Increased aqueous autotaxin and lysophosphatidic acid levels are potential prognostic factors after trabeculectomy in different types of glaucoma. Sci Rep. 8: 11304, 2018.
  9. Iino, H., Okano, T., Daimon, M., Sasaki, K., Chigira, M., Nakao, T., Mizuno, Y., Yamazaki, T., Kurano, M., Yatomi, Y., Sumi, Y., Sasano, T., and Miyata, T. Usefulness of Carotid Arterial Strain Values for Evaluating the Arteriosclerosis. J. Atheroscler Thromb. , in press.
  10. Kurano M, Hasegawa K, Kunimi M, Hara M, Yatomi Y, Teramoto T, and Tsukamoto K.Sitosterol prevents obesity-related chronic inflammation. Biochim. Biophys. Acta 1863: 191-198, 2018.
  11. Kurano, M., Miyagaki, T., Miyagawa, T., Igarashi, K., Shimamoto, S., Ikeda, H., Aoki, J., Sato, S., and Yatomi Y. Association between serum autotaxin or phosphatidylserine-specific phospholipase A1 levels and melanoma. J. Dermatol. 45: 571-579, 2018.
  12. Kurano, M., Tsuneyama, K., Morimoto, Y., Shimizu, T., Jona, M., Kassai, H.,Nakao, K., Aiba, A., and Yatomi, Y. Apolipoprotein M Protects Lipopolysaccharide-Treated Mice from Death and Organ Injury. Thromb Haemost. 118: 1021-1035, 2018.
  13. Kurano, M., Ikeda, H., Iso-O, N., Hara, M., Tsukamoto, K., and Yatomi, Y. Regulation of the metabolism of apolipoprotein M and sphingosine 1-phosphate by hepatic PPARγ activity. Biochem. J. 475: 2009-2024, 2018.
  14. Lee, S.C., Daimon, M., Di Tullio, M.R., Homma, S., Hasegawa, T., Chiou, S.H., Nakao, T., Hirokawa, M., Mizuno, Y., Yatomi, Y., Yamazaki, T., and Komuro I. Beneficial effect of body weight control on left ventricular diastolic function in the general population: an analysis of longitudinal data from a health check-up clinic. Eur. Heart J. Cardiovasc. Imaging 19: 136-142, 2018.
  15. Lei, C., Kobayashi, H., Wu, Y., Li, M., Isozaki, A., Yasumoto, A., Mikami, H., Ito, T., Nitta, N., Sugimura, T., Yamada, M., Yatomi, Y., Di Carlo, D., Ozeki, Y., and Goda, K. High-throughput imaging flow cytometry by optofluidic time-stretch microscopy. Nat. Protoc. 13: 1603-1631, 2018.
  16. Maemura, K., Watanabe, K., Ando, T., Hiyama, N., Sakatani, T., Amano, Y., Kage, H., Nakajima, J., Yatomi, Y., Nagase, T., and Takai D. Altered editing level of microRNAs is a potential biomarker in lung adenocarcinoma. Cancer Sci., in press.
  17. Makita, K., Mikami, Y., Matsuzaki, H., Narumoto, O., Takai, D., Yatomi, Y., and Nagase, T. Utility of bronchoscopy in the definitive diagnosis of patients with haematological malignancies presenting with radiological abnormalities. Clin. Respir. J. 12: 1381-1388, 2018.
  18. Mishima, Y., Kurano, M., Kobayashi, T., Nishikawa, M., Ohkawa, R., Tozuka, M., and Yatomi, Y. Dihydro-sphingosine 1-phosphate interacts with carrier proteins in a manner distinct from that of sphingosine 1-phosphate. Biosci Rep. 38: BSR20181288, 2018.
  19. Murono, K., Ishihara, S., Kawai, K., Kaneko, M., Sasaki, K., Otani, K., Yasuda, K., Nishikawa, T., Tanaka, T., Kiyomatsu, T., Hata, K., Nozawa, H., Satoh, Y., Kurihara, M., Yatomi, Y., and Watanabe, T. Significance of carcinoembryonic antigen mRNA in peritoneal lavage determined by transcription-reverse transcription concerted method in patients with low rectal cancer. Asian J. Surg. 41: 321-327, 2018.
  20. Nakao, T., Yasumoto, A., Tokuoka, S., Kita, Y., Kawahara, T., Daimon, M., and Yatomi Y. The impact of night-shift work on platelet function in healthy medical staff. J. Occup. Health. 60: 324-332, 2018.
  21. Nakatsuka, T., Soroida, Y., Nakagawa, H., Shindo, T., Sato, M., Soma, K., Nakagomi, R., Kobayashi, T., Endo, M., Hikita, H., Sato, M., Gotoh, H., Iwai, T., Yasui, M., Shinozaki-Ushiku, A., Shiraga, K., Asakai, H., Hirata, Y., Fukayama, M., Ikeda, H., Yatomi, Y., Tateishi, R., Inuzuka, R., and Koike, K. Identification of Liver Fibrosis Using the Hepatic Vein Waveform in Patients with Fontan Circulation. Hepatol Res. , in press.
  22. Nitta, N., Sugimura, T., Isozaki, A., Mikami, H., Hiraki, K., Sakuma, S., Iino, T., Arai, F., Endo, T., Fujiwaki, Y., Fukuzawa, H., Hase, M., Hayakawa, T., Hiramatsu, K., Hoshino, Y., Inaba, M., Ito, T., Karakawa, H., Kasai, Y., Koizumi, K., Lee, S., Lei, C., Li, M., Maeno, T., Matsusaka, S., Murakami, D., Nakagawa, A., Oguchi, Y., Oikawa, M., Ota, T., Shiba, K., Shintaku, H., Shirasaki, Y., Suga, K., Suzuki, Y., Suzuki, N., Tanaka, Y., Tezuka, H., Toyokawa, C., Yalikun, Y., Yamada, M., Yamagishi, M., Yamano, T., Yasumoto, A., Yatomi, Y., Yazawa, M., Di., Carlo, D., Hosokawa, Y., Uemura, S., Ozeki, Y., and Goda, K. Intelligent Image-Activated Cell Sorting. Cell, in press. Press Release.
  23. Ohkawa, R., Kurano, M., Sakai, N., Kishimoto, T., Nojiri, T., Igarashi, K., Hosogaya, S., Ozaki, Y., Dohi, T., Miyauchi, K., Daida, H., Aoki, J., Okubo, S., Ikeda, H., Tozuka, M., and Yatomi Y. Measurement of plasma choline in acute coronary syndrome: importance of suitable sampling conditions for this assay. Sci. Rep. 8: 4725, 2018.
  24. Sasada, K., Yamamoto, N., Masuda, H., Tanaka, Y., Ishihara, A., Takamatsu, Y., Yatomi, Y., Katsuda, W., Sato, I., and Matsui, H. Inter-observer variance and the need for standardization in the morphological classification of myelodysplastic syndrome. Leuk. Res. 69: 54-59, 2018.
  25. Sakoda, M., Kaneko, M., Ohta, S., Qi, P., Ichimura, S., Yatomi, Y., and Ito, T. An Injectable Hemostat Composed of a Polyphosphate-Conjugated Hyaluronan Hydrogel. Biomacromolecules. 19: 3280-3290, 2018.
  26. Sato, M., Ohkawa, R., Low, H., Nishimori, M., Okubo, S., Yoshimoto, A., Yano, K., Kameda, T., Yatomi, Y., and Tozuka, M. Serum amyloid A does not affect high-density lipoprotein cholesterol measurement by a homogeneous assay. Clin Biochem., in press.
  27. Shimizu,K., Soroida, Y., Sato, M., Hikita, H., Kobayashi, T., Endo, M., Sato, M., Gotoh, H., Iwai, T., Tateishi, R., Koike, K., Yatomi, Y., and Ikeda H. Eradication of hepatitis C virus is associated with the attenuation of steatosis as evaluated using a controlled attenuation parameter. Sci. Rep. 8: 7845, 2018.
  28. Tokuhara, Y., Shukuya, K., Tanaka, M., Sogabe, K., Ejima, Y., Hosokawa, S., Ohsaki, H., Morinishi, T., Hirakawa, E., Yatomi, Y., and Shimosawa T.  Absorbance measurements of oxidation of homogentisic acid accelerated by the addition of alkaline solution with sodium hypochlorite pentahydrate. Sci Rep. 8: 11364, 2018.
  29. Uranbileg, B., Nishikawa, T., Ikeda, H., Kurano, M., Sato, M., Saigusa, D., Aoki, J., Watanabe, T., and Yatomi, Y. Evidence Suggests Sphingosine 1-Phosphate Might Be Actively Generated, Degraded, and Transported to Extracellular Spaces With Increased S1P2 and S1P3 Expression in Colon Cancer. Clin. Colorectal Cancer 17: e171-e182, 2018.
  30. Watanabe, K., Yasumoto, A., Amano, Y., Kage, H., Goto, Y., Yatomi, Y., Takai, D., and Nagase, T. Mean platelet volume and lymphocyte-to-monocyte ratio are associated with shorter progression-free survival in EGFR-mutant lung adenocarcinoma treated by EGFR tyrosine kinase inhibitor. PLoS One. 13: e0203625, 2018.
  31. Yasukawa, K., Shimosawa, T., Okubo, S., and Yatomi, Y. ANNALS EXPRESS: A simple, rapid, and validated high-performance liquid chromatography method suitable for clinical measurements of human mercaptalbumin and nonmercaptalbumin. Ann. Clin. Biochem. 55: 121-127, 2018.
  32. Yasunaga, M., Taoka, K., Nakagawa, H., Yamada, A., Abe, H., Jona, M., Nishikawa, M., Nakazaki, K., Yatomi, Y., Fukayama, M., Koike, K., and Kurokawa, M. Eculizumab treatment for ischemic enteritis accompanied with paroxysmal nocturnal hemoglobinuria: a case report and literature review. Ann. Hematol. 97: 1513-1515, 2018.
  33. Xu, B., Kawata, T., Daimon, M., Kimura, K., Nakao, T., Lee, S.C., Hirokawa, M., Yoshinaga, A., Watanabe, M., Yatomi, Y., and Komuro I. Prognostic Value of a Simple Echocardiographic Parameter, the Right Ventricular Systolic to Diastolic Duration Ratio, in Patients with Advanced Heart Failure with Non-Ischemic Dilated Cardiomyopathy. Int. Heart J. , inpress.


  1. Guo, B., Lei, C., Wu, Y., Kobayashi, H., Ito, T., Yalikun, Y., Lee, S., Isozaki, A., Li, M., Jiang, Y., Yasumoto, A., Di, Carlo. D., Tanaka, Y., Yatomi, Y., Ozeki, Y., and Goda, K., Optofluidic time-stretch quantitative phase microscopy. Methods 136: 116-125, 2018.
  2. Kurano, M. and Yatomi, Y. Sphingosine 1-Phosphate and Atherosclerosis. J. Atheroscler Thromb. 25: 16-26, 2018.

International Conference Presentations

  1. Kageyama, Y., Miyamoto, K., Yanagida, M., and Sakanaka, C. How can we contribute to innovative drug development? ~From our experience in participating global study. The 18th World Congress of Basic and Clinical Pharmacology (WCP2018). 2018. 7. 1-6. Kyoto, Japan.ß
  2. Morita, Y., Shukuya, K., Tanaka, M., Hisasue, T., Sato,M., Sone, S., Kurano, M., and Yatomi, Y. Development and effectiveness of full-automated urinalysis system using urine aliquot processor. Cherry blossom symposium 2018. 2018. 4. 19-21. Morioka, Japan. Poster presentation
  3. Yatomi, Y. Accreditation of Medical Laboratories in Japan. 2018 Asia Pacific Laboratory Accreditation Cooperation (APLAC)/ Pacific Accreditation Cooperation (PAC) Joint Annual Meetings. 2018. 6. 1-9. Kyoto, Japan.
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